Dec 2024 – now
Project manager at Saman Health Insurance: Data structure
Nov – Dec 2024
Associate product owner at Intelligent Health Platform
Sep – Oct 2024
Digital transformation consultant at a private hospital
2024
MSc of Medical Education graduation
2023 – 2025
Postdoctoral research fellow at the Icahn School of Medicine
Mar – Dec 2021
Research associate at AI-Med co. (AI-based brain CT scan analysis)
2021-2023
Research Fellow at the Research Institute for Gastroenterology and Liver Diseases
2021
MD-MBA graduation
2019 – 2022
Co-founder of Medic-AI
2018 – 2024
Programming Experience
Python - LLM
Python - AI & Vision
Unix - Server Setup
2018 – 2024
Mentorship Experience
2016 – 2024
Research Journey
Publications
Savage T; Wang J; Gallo R; Boukil A; Patel V; Safavi-Naini SAA; Soroush A; Chen JH, 2025. Large language model uncertainty proxies: discrimination and calibration for medical diagnosis and treatment.  J Am Med Inform Assoc 32(1):139-149
Raoufi M; Hojabri M; Samiei Nasr D; Najafiarab H; Salahi-Niri A; Ebrahimi N; Ariana S; Khodabandeh H; Salarian S; Looha MA; Pourhoseingholi MA; Safavi-Naini SAA, 2024. Comparative analysis of COVID-19 pneumonia in pregnant versus matched non-pregnant women: radiologic, laboratory, and clinical perspectives.  Sci Rep 14(1):22609
Karout L; Kalra MK, 2024. Survey of CT radiation doses and iodinated contrast medium administration: an international multicentric study.  Eur Radiol.
Allahgholipour A; Safavi-Naini SAA; Shekarriz Foomany Z; Eskandari A; Nazari Rostami H; Honarvar MJ; Mohammadi M; Khalili P; Ilaghi M; Afshar H; Amini Baghbadorani A; Moghimi HR; Chamani Goorabi A; Mehrparvar A; Safari M; Nakhli AS; Mahmoudabadi M; Seifadini A; Sheikhansari S; Khojastehfar S; Mahdavi P; Mohammadi M; Ashrafi Barzideh S; Akbarzadeh N; Delavarpour Moghadam SH; Tavakoli Pirzaman A; Barary M; Emamhadi M, 2024. COVID-19 vaccines breakthrough infection and adverse reactions in medical students: a nationwide survey in Iran.  Front Public Health 12:1348015
Khalili S; Safavi-Naini SAA; Zarand P; Masoumi S; Farsi Y; Hosseinpanah F; Azizi F, 2024. Metabolic health’s central role in chronic kidney disease progression: a 20-year study of obesity-metabolic phenotype transitions.  Sci Rep 14(1):5244
Safavi-Naini SAA; Sobhani S; Malekpour MR; Bhalla K; Shahraz S; Haghshenas R; Ghamari SH; Abbasi-Kangevari M; Rezaei N; Heydari ST; Rezaei N; Lankarani KB; Farzadfar F, 2024. Drivers’ behavior confronting fixed and point-to-point speed enforcement camera: agent-based simulation and translation to crash relative risk change.  Sci Rep 14(1):1863
Pourhoseingholi MA; Yazdani O; Azizmohammad Looha M; Safavi-Naini SAA; Esbati R; Ilkhani S; Taraghikhah N; Hatamabadi H; Sadeghi A; Heidari K; Namazi N; Asadimanesh N; Hatari S; Shahrokh S; Solhpour A; Jamialahmadi T; Santos RD; Sahebkar A, 2024. Atorvastatin Effect on COVID-19 Outcomes: A Propensity Score Matched Study on Hospitalized Patients.  Curr Med Chem.
Nekooghadam SM; Bozorgmehr R; Safavi-Naini SAA, 2023. Acrocyanosis and Progressive Skin Necrosis as Manifestation of Waldenstrom Macroglobulinemia Associated With Type I Cryoglobulinemia: A Case Report.  Int J Low Extrem Wounds 22(3):605-609
Safavi Naini A; Rostami MM; Shojaeian F; Azizmohammad Looha M; Ghanbari Motlagh A; Safavi AA; Safavi-Naini SAA, 2023. Epidemiology and Histopathology of Nasopharyngeal Neoplasms in Iran.  Iran J Otorhinolaryngol 35(126):3-12
Barough SS; Safavi-Naini SAA; Siavoshi F; Tamimi A; Ilkhani S; Akbari S; Ezzati S; Hatamabadi H; Pourhoseingholi MA, 2023. Generalizable machine learning approach for COVID-19 mortality risk prediction using on-admission clinical and laboratory features.  Sci Rep 13(1):2399
Siavoshi F; Safavi-Naini SAA; Shirzadeh Barough S; Azizmohammad Looha M; Hatamabadi H; Ommi D; Jalili Khoshnoud R; Fatemi A; Pourhoseingholi MA, 2023. On-admission and dynamic trend of laboratory profiles as prognostic biomarkers in COVID-19 inpatients.  Sci Rep 13(1):6993
Hatami H; Jamshidi P; Arbabi M; Safavi-Naini SAA; Farokh P; Izadi-Jorshari G; Mohammadzadeh B; Nasiri MJ; Zandi M; Nayebzade A; Sechi LA, 2023. Demographic, Epidemiologic, and Clinical Characteristics of Human Monkeypox Disease Pre- and Post-2022 Outbreaks: A Systematic Review and Meta-Analysis.  Biomedicines 11.
Azizi N; Zangiabadian M; Seifi G; Davari A; Yekekhani E; Safavi-Naini SAA; Berger NA; Nasiri MJ; Sohrabi MR, 2023. Gastric Cancer Risk in Association with Underweight, Overweight, and Obesity: A Systematic Review and Meta-Analysis.  Cancers (Basel) 15.
Pourhoseingholi MA; Javazm AR; Asadimanesh N; Shojaeian F; Looha MA; Safavi-Naini SAA; Mohammadzadeh B; Jamshidi P; Gholampoor F; Yazdani O; Zameni N; Azizan Z; Sahebkar A, 2023. Effect of interferon-α on COVID-19 in-hospital mortality: a large-scale propensity score-matched study.  Eur Cytokine Netw 34(2):10-19
Tehrani SSM; Zarvani M; Amiri P; Ghods Z; Raoufi M; Safavi-Naini SAA; Soheili A; Gharib M; Abbasi H, 2023. Visual transformer and deep CNN prediction of high-risk COVID-19 infected patients using fusion of CT images and clinical data.  BMC Med Inform Decis Mak 23(1):265
Sabaghian T; Honarvar M; Safavi-Naini SAA; Sadeghi Fadaki AS; Pourhoseingholi MA; Hatamabadi H, 2022. Effect of Electrolyte Imbalance on Mortality and Late Acute Kidney Injury in Hospitalized COVID-19 Patients.  Iran J Kidney Dis 16(4):228-237
Safavi-Naini SAA; Pourhoseingholi MA, 2022. The early impact of COVID-19 vaccination on deaths among elderly people in Iran.  Gastroenterol Hepatol Bed Bench 15(2):103-105
Hatamabadi H; Sabaghian T; Sadeghi A; Heidari K; Safavi-Naini SAA; Looha MA; Taraghikhah N; Khalili S; Karrabi K; Saffarian A; Shahsavan S; Majlesi H; Allahgholipour Komleh A; Hatari S; Zameni N; Ilkhani S; Hajimirzaei SM; Ghaffari A; Fallah MM; Kalantar R; Naderi N; Bahmaei P; Asadimanesh N; Esbati R; Yazdani O; Shojaeian F; Azizan Z; Ebrahimi N; Jafarzade F; Soheili A; Gholampoor F; Namazi N; Solhpour A; Jamialahamdi T; Pourhoseingholi MA; Sahebkar A, 2022. Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes.  Biomed Res Int 2022:2350063
Safavi-Naini SAA; Farsi Y; Alali WQ; Solhpour A; Pourhoseingholi MA, 2022. Excess all-cause mortality and COVID-19 reported fatality in Iran (April 2013-September 2021): age and sex disaggregated time series analysis.  BMC Res Notes 15(1):130
Raoufi M; Safavi Naini SAA; Azizan Z; Jafar Zade F; Shojaeian F; Ghanbari Boroujeni M; Robatjazi F; Haghighi M; Arhami Dolatabadi A; Soleimantabar H; Shoaee S; Hatamabadi H, 2020. Correlation between Chest Computed Tomography Scan Findings and Mortality of COVID-19 Cases; a Cross sectional Study.  Arch Acad Emerg Med 8(1):e57
Publication list retrieved from NCBI using ImpactPubs
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Peer Reviews
Actively contributed to the academic community by completing a total of 39 reviews for 16 different publications and grants. His extensive peer review work spans a range of reputable journals, including:
• Acta Endocrinologica: 1 review
• Aging: 4 reviews
• Autoimmune Diseases: 1 review
• BMC Public Health: 1 review
• Frontiers in Genetics: 1 review
• Frontiers in Oncology: 1 review
• Frontiers in Public Health: 4 reviews
• Gastroenterology and Hepatology From Bed to Bench: 2 reviews
• International Journal of Surgery: 12 reviews
• IUBMB Life: 1 review
• JMIR Public Health and Surveillance: 1 review
• JMIR: 1 review
• Journal of Clinical Laboratory Analysis: 1 review
• PLOS ONE: 6 reviews
• The Journal of Clinical Endocrinology & Metabolism: 1 review
• The Journal of Clinical Endocrinology and Metabolism: 1 review
Positions
- [2023-2025] Postdoctoral Researcher
- Projects:
- Benchmarking LLMs and VLMs on gastroenterology
- Enhancing explainability through certainty quantification
- Early detection and screening of upper GI cancers
- Projects:
- [2021-2023] Research Fellow at Research Institute for Gastroenterology and Liver Diseases, SBMU
- Projects:
- Founder of PanCanAID: screening, early detection, treatment planning, resectability scoring, prognose prediction
- Capsule endoscopy repository
- EUS repository
- COVID-19 CDSS
- Projects:
- [2018-2021] Research Associate at Research Institute for Gastroenterology and Liver Diseases, SBMU
- Projects: Projects: Lead coordinator of COVID-19 research in a multi-centric project involving 6 medical centers leading to collection of data from 10,000 inpatients with 1,500 follow-ups
- Role: Team lead, programming, study design, automation, data analyst
- [2017] Research Associate at National Research Institute of Tuberculosis and Lung Disease, SBMU:
- Projects: Time series analysis of National Cancer Registry database for nasopharyngeal and oropharyngeal cancers.
- Role: Data analysis and curation (MD thesis)
2014 – 2021
Education and Med School
University Entrance Exam
Ranked 555th out of over 500,000 students in the university entrance exam and began my 8-year MD program at Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Research Experience
- Started my thesis using the national cancer registry database to investigate trends in oral cavity and oropharyngeal cancer, searching for clues on HPV’s impact—given that it is a risk factor for one but not the other.
- Joined the Student Research Committee and founded the School of Medicine Students’ Journal.
- Contributed to two research projects:
- Led the Tehran-COVID-Cohort, overseeing data collection from five centers and developing automated data curation scripts.
- In my final year of medical school, I founded PanCanAID.
Clinical Experience
- Completed an 18-month hands-on internship followed by two months of supervised practice.
- During the COVID-19 pandemic, my internship included one month in the ICU, one month in the ward, and one month in the ER.
- Shadowing advanced endoscopic procedures.
Medical Education (MSc)
- Medalist in the National Olympiad of Medical Sciences for my project on medical education: developing a virtual patient for educational support.
- I had the opportunity to pursue a double major, earning a Master of Science in Medical Education (2020–2023).
- Thesis A: Evaluated the impact of using the virtual patient platform (CyberPatient) in a ‘Digestive Disease Bootcamp’ for medical externs.
- Thesis B: Developed an LLM-based question generation system using validated sources and retrieval-augmented generation techniques.”
Health-MBA
During medical school, my passion for teamwork and leadership drove me to deepen my understanding of project management. This led me to pursue:
- Master of Business Administration in Healthcare at SBMU (200-hour program, 12 courses, GPA: 20/20)
- Master of Business Administration at University of Tehran, College of Engineering (250-hour program, 13 courses, GPA: 17/20)”